An Amtrak train traveling between New York and Miami collided with a freight train on Sunday morning, killing at least two people and injuring at least 50 others, according to police officials.
Amtrak said Train 91, which was carrying eight crew members and 139 passengers, collided with a CSX train near Cayce, S.C., around 2:35 a.m., leaving several people injured.
“The lead engine derailed, as well as some passenger cars” after the impact, Amtrak said in a statement.
The Lexington County Sheriff’s Department in South Carolina said on Twitter that at least two people had been killed and that emergency crews were tending to at least 50 injured.
The Red Cross said on Twitter that “disaster trained volunteers” were responding to the scene of the accident. And the South Carolina Emergency Management Division, which was responding, said the accident occurred near Pine Ridge, S.C.
It was the second major crash for the railroad in less than a week. On Wednesday, a train carrying Republican members of Congress to a retreat in West Virginia hit a garbage truck in rural Virginia, killing a passenger in the truck.
Two other passengers from the truck were injured — one seriously — and hospitalized. Two members of the train’s crew and at least two passengers, including Representative Jason Lewis, Republican of Minnesota, were also hospitalized with minor injuries.
Republicans had chartered the train to carry them from Washington to the Greenbrier resort in West Virginia, where the party was holding its annual policy retreat. Several lawmakers who were aboard the train estimated that more than half of the Republican members of the House and Senate, including Speaker Paul D. Ryan, were on board, and that many were accompanied by their spouses.
In December, a passenger train on a newly opened Amtrak route jumped the tracks on an overpass south of Tacoma, Wash., slamming rail cars into a busy highway, killing at least three people and injuring about 100 others.
In 2015, an Amtrak train derailed in Philadelphia, killing eight people and injuring more than 200. A Pennsylvania judge dismissed involuntary manslaughter charges against the Amtrak engineer, saying it appeared to be an accident and not the result of criminal negligence.